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KU Center for Technology Commercialization

    Innovation Sphere


  • Qiang Ye
  • Paulette Spencer
  • Elizabeth Topp
  • Jonggu Park



Project TitleWater-Compatible Dentin Adhesives with Esterase Resistance
Track Code08KU022L
Short Description

The invention is a new dentin adhesive that has a high tolerance to water and enhanced resistance to esterase degradation that could increase the clinical lifetime of restorative composites.

Tagsdentin adhesive, Dental Composite, Dental Bonding, dentistry
Posted DateSep 3, 2013 12:17 PM


Qiang Ye
Paulette Spencer
Elizabeth Topp
Jonggu Park


Matthew Koenig


The monomer can be used in dental composite restorative materials, pit and fissure sealants, and adhesive resin cements for dentistry.


The use of restorative composites in dentistry has been driven by esthetic features and the public’s concern about mercury release from dental amalgam. Although there is great demand for dentin adhesives that are mercury free, current mercury free adhesives on the market exhibit a short clinical lifetime due to the presence of water and enzymatic degradation in the mouth. The primary factor in the premature failure of composite restorations is recurrent caries at the margins of these restorations. Recurrent decay is most often localized gingivally and is linked to the lack of consistent seal at the tooth/material interface. Water in the mouth is a major interfering factor when bonding adhesives and/or composites to the tooth. Effective bonding at the prepared tooth/composite material interface requires dentin adhesives that provide superior properties and rapid polymerization under clinical conditions.

Why it is better

The new methacrylate based dentin adhesive uses a new monomer which has shown improved resistance to esterase degradation without compromising other physical properties such as degree of conversion, adhesive penetration and thermal and mechanical properties. The monomer was designed to have better biodegradation performance in the moist environment of the mouth.

Contact Information

Matt Koenig, J.D.

KU Center for Technology Commercialization (785) 864-1774

Intellectual Property

Patent Number Issue Date Type Country of Filing
US8344041 None Utility United States

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